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Updated: May 30, 2026

Multispectral Optoacoustic Tomography for Functional Imaging in Vascular Research
Published on: June 8, 2022
Qualitative near-infrared vascular imaging system with tuned aperture computed tomography
Tatsuhiko Matsushita1, Tosiaki Miyati, Kazuya Nakayama
1Kanazawa University, Graduate School of Medical Science, Division of Health Science, 5-11-80 Kodatsuno, Kanazawa, 920-0942, Japan. tmatusi@mhs.mp.kanazawa-u.ac.jp
Abstract:
We developed a novel system for imaging and qualitatively analyzing the surface vessels using near-infrared (NIR) radiation using tuned aperture computed tomography (TACT(®)). The system consisted of a NIR-sensitive CCD camera surrounded by sixty light emitting diodes (with wavelengths alternating between 700 or 810 nm). This system produced thin NIR tomograms, under 0.5 mm in slice thickness. The venous oxygenation index reflecting oxygen saturation levels calculated from NIR tomograms was more sensitive than that from the NIR images. This novel system makes it possible to noninvasively obtain NIR tomograms and accurately analyze changes in oxygen saturation.
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