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Epigenetic mechanisms regulating neural development and pediatric brain tumor formation

Claudia M C Faria1, James T Rutka, Christian Smith

  • 1Division of Neurosurgery, Department of Surgery, The University of Toronto, Ontario, Canada.

Journal of Neurosurgery. Pediatrics
|August 3, 2011
PubMed
Summary

Epigenetic dysregulation in pediatric brain tumors, particularly embryonal tumors, contributes to poor outcomes. Understanding these epigenetic changes offers potential for novel treatment strategies in children.

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