Related Experiment Video
Updated: May 30, 2026
Optimization of the Epimedii Folium Mutton-Oil Processing Technology and Testing Its Effect on Zebrafish Embryonic Development
Published on: March 17, 2023
[Study on the extraction of total alkaloid from folium nelumbinis with ultrasonic wave technology optimized by
Fu-gang Wang1, Juan Cao, Bin Liu
1College of pharmacy, Taishan Medical University, Taian 271016, China. wfg713@sina.com
Objective:
To optimize the extracting process of Folium Nelumbinis by central composite design and response surface method.
Methods:
Independent variables were ethanol concentration, solvents ratio and pH,dependent variable was extracting rate of alkaloid. Composite design and response surface method were used to optimize the extracting process. Resultant model was used to predict the response in the optimal region.
Results:
The optimum extraction conditions were 80% aqueous ethanol, 75 fold solvent, pH value 5.
Conclusion:
The optimum process is simple and more convenient for extracting Folium Nelumbinis. The observed and predicted values are close to each other.
