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Updated: May 30, 2026
10:27
Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
Published on: December 15, 2011
Erythema elevatum diutinum: an "idiopathic" case
Nadia El Fekih1, Ikram Belgith, Bécima Fazaa
1Departement of Dermatology, Charles Nicolle Hospital, Tunis, Tunisia.
Dermatology Online Journal
|August 4, 2011
Summary
Erythema elevatum diutinum (EED) is a rare leukocytoclastic vasculitis. This case report highlights a patient successfully treated with dapsone, showing its efficacy in managing EED symptoms.
Area of Science:
- Dermatology
- Pathology
Background:
- Erythema elevatum diutinum (EED) is a rare neutrophilic dermatosis with uncertain pathogenesis.
- It is now classified as leukocytoclastic vasculitis based on histopathology.
- Various clinical presentations and associated conditions are documented.
Observation:
- A 58-year-old male presented with a three-month history of plaques and nodules.
- Lesions were located on extensor surfaces including hands, elbows, knees, ankles, forearms, and buttocks.
- Histopathology revealed leukocytoclastic vasculitis, consistent with EED.
Findings:
- Diagnostic workup for associated paraproteinemia or solid cancer was negative.
- Treatment with dapsone resulted in symptom improvement within weeks.
Implications:
- This case reinforces the diagnosis of EED based on clinical and histological findings.
- Dapsone demonstrates effectiveness in treating EED.
- Further research into EED pathogenesis and associated conditions is warranted.
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