[Pathogenetic endocrine aspects of primary osteoporosis]

The pathogenetic endocrine aspects of primary osteoporosis are reviewed on the basis of some physiological remarks. Specifically, postmenopausal and senile osteoporosis represent 2 distinct clinical entities. For both, the last event in the pathogenetic chain is in any case the negative skeletal balance, but the starting point and the development of processes present differently.