Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence for early, clinically silent medial temporal lobe inflammation after CAR-T cell therapy.

European journal of cancer (Oxford, England : 1990)·2026
Same author

Thermal and imaging effects of Feraheme in MR-guided focused ultrasound: a phantom study.

Physics in medicine and biology·2026
Same author

Individualized phenotyping of functional amyotrophic lateral sclerosis pathology in sensorimotor cortex.

Brain communications·2026
Same author

Cerebral Oxygen Budgeting: Network-Level BOLD Dynamics During Acute Hypoxia.

bioRxiv : the preprint server for biology·2026
Same author

Phase-constrained zero-shot self-supervised learning for BLADE liver MRI reconstruction.

Magma (New York, N.Y.)·2026
Same author

Author Correction: Human cerebrospinal fluid net flow enhanced by respiration during the awake state.

Nature communications·2026

Related Experiment Video

Updated: May 30, 2026

Medical-grade Sterilizable Target for Fluid-immersed Fetoscope Optical Distortion Calibration
07:03

Medical-grade Sterilizable Target for Fluid-immersed Fetoscope Optical Distortion Calibration

Published on: February 23, 2017

Highly accelerated PSF-mapping for EPI distortion correction with improved fidelity.

Myung-Ho In1, Oliver Speck

  • 1Department of Biomedical Magnetic Resonance, Institute for Experimental Physics, Otto-von-Guericke University Magdeburg, Magdeburg, Germany. myung-ho.in@ovgu.de

Magma (New York, N.Y.)
|August 5, 2011
PubMed
Summary

This study introduces an improved method for correcting echo-planar imaging (EPI) distortions using point-spread-function (PSF) mapping. The technique accelerates data acquisition without compromising image quality or reliability.

More Related Videos

In vivo Imaging of Biological Tissues with Combined Two-Photon Fluorescence and Stimulated Raman Scattering Microscopy
09:06

In vivo Imaging of Biological Tissues with Combined Two-Photon Fluorescence and Stimulated Raman Scattering Microscopy

Published on: December 20, 2021

Related Experiment Videos

Last Updated: May 30, 2026

Medical-grade Sterilizable Target for Fluid-immersed Fetoscope Optical Distortion Calibration
07:03

Medical-grade Sterilizable Target for Fluid-immersed Fetoscope Optical Distortion Calibration

Published on: February 23, 2017

In vivo Imaging of Biological Tissues with Combined Two-Photon Fluorescence and Stimulated Raman Scattering Microscopy
09:06

In vivo Imaging of Biological Tissues with Combined Two-Photon Fluorescence and Stimulated Raman Scattering Microscopy

Published on: December 20, 2021

Area of Science:

  • Magnetic Resonance Imaging
  • Image Processing

Background:

  • Geometric distortions in echo-planar imaging (EPI) are a significant challenge in neuroimaging.
  • Accurate distortion correction is crucial for reliable fMRI and diffusion imaging analysis.

Purpose of the Study:

  • To present an improved point-spread-function (PSF) mapping-based distortion correction method for EPI.
  • To accelerate PSF acquisition for distortion correction without sacrificing quality or reliability.

Main Methods:

  • Measured the EPI-PSF in EPI phase-encoding coordinates as a kernel for distortion correction.
  • Applied FOV reduction in the PSF mapping dimension for accelerated acquisition.
  • Introduced a novel fold-over artifact correction method for the reduced dimension.
  • Compared the proposed accelerated method with full encoding and existing interpolation techniques in phantoms and human brain imaging at 7T.

Main Results:

  • The proposed method accurately corrects geometric distortions in EPI with high quality, even with significant acceleration.
  • Unlike partial parallel imaging, this method does not introduce noise enhancement.
  • The accelerated acquisition and computation of PSF reference data are significantly improved.

Conclusions:

  • The EPI-PSF-based distortion correction method enhances the accuracy of EPI distortion correction.
  • The developed technique accelerates the acquisition and computation of PSF reference data, making it more efficient.