Related Experiment Video
Updated: Aug 18, 2026

05:51
Production of Germ-Free Fast-Growing Broilers from a Commercial Line for Microbiota Studies
Published on: June 18, 2020
[The origins of the gnotobiotic technic--Küster/Nuttall/Schottelius/ Thierfelder]
1Zentralinstitut für Mikrobiologie und Experimentelle Therapie, Akademie der Wissenschaften, DDR, Jena.
Abstract:
The first experiment to create germfree animals was done by NUTTALL and THIERFELDER in 1985. Later on, KUSTER (1912) published an apparatus which became the prototype for all following isolators. Another system was developed by SCHOTTELIUS in 1899, which became the prototype of the so-called "clean-room principle".

