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Updated: May 30, 2026
Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
[Studies on flavonoids from the leaves of Lindera aggregata]
Mei Xiao1, Ning Cao, Jing-jing Fan
1State Key Laboratory of Pharmaceutical Biotechnology,School of Life Sciences, Nanjing University, Nanjing 210093, China. freefly_xm@163.com
Objective:
To investigate the chemical constituents in the leaves of Lindera aggregate.
Methods:
Compounds were separated by column chromatography with silica gel and ODS. The structures were identified by physicochemical properties and spectral analysis (1H-NMR, 13C-NMR).
Results:
Eight compounds were isolated and identified as: quercetin-3-O-L-rhamnoside(1), kaempferol-3-O-L-rhamnoside(2), kaempferol(3), dihydrokaempferol-3-O-L-rhamnoside (4), quercetin (5), quercetin-3-O-alpha-D-arabinofuranoside (6), quercetin-3-O-alpha-D-glucopyranoside(7), kaempferol-3-O-D-glucopyranoside(8).
Conclusion:
Compounds 2,4 and 8 are obtained from Lindera aggregata for the first time.
