Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 30, 2026

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
10:51

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats

Published on: May 11, 2018

Transcranial electrical stimulation (tES - tDCS; tRNS, tACS) methods.

Walter Paulus1

  • 1Department of Clinical Neurophysiology, University Medical Faculty Göttingen, Göttingen, Germany. wpaulus@med.uni-goettingen.de

Neuropsychological Rehabilitation
|August 9, 2011
PubMed
Summary

Weak transcranial direct current stimulation (tDCS) and related techniques can alter brain excitability and induce neuroplastic effects. These methods offer promising avenues for non-invasive brain modulation, with outcomes influenced by stimulation parameters and drug interactions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Confounding factors in the comparison of iTBS protocols - Comments on Ramdeo et al.: "Waveform matters".

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

IFCN position statement: use of artificial intelligence in clinical neurophysiology.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Impaired interhemispheric inhibition in isolated REM sleep behavior disorder: first exploratory transcranial magnetic stimulation-based evidence.

Sleep·2026
Same author

Memories of Mark. Personal reflections by those in IFCN who worked with Mark Hallett.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines (2017-2025: An update) - endorsed by the European Society for Brain Stimulation (ESBS) and by the International Federation for Clinical Neurophysiology (IFCN).

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
Same author

Negative Affective Traits Moderate Transcranial Direct Current Stimulation Effects on Memory.

Biological psychiatry. Cognitive neuroscience and neuroimaging·2025

Area of Science:

  • Neuroscience
  • Neuromodulation

Background:

  • Transcranial direct current stimulation (tDCS) uses weak electrical fields (~1 mA) to induce long-lasting brain changes.
  • tDCS modulates brain excitability through membrane polarization (anodal depolarization, cathodal hyperpolarization).

Purpose of the Study:

  • To review the mechanisms and influencing factors of tDCS, tACS, and tRNS.
  • To highlight the potential of non-invasive brain stimulation for inducing neuroplasticity.

Main Methods:

  • Review of existing literature on tDCS, transcranial alternating current stimulation (tACS), and transcranial random noise stimulation (tRNS).
  • Discussion of key stimulation parameters: polarity, duration, intensity, and drug interactions.

Main Results:

More Related Videos

Transcranial Electrical Brain Stimulation in Alert Rodents
10:08

Transcranial Electrical Brain Stimulation in Alert Rodents

Published on: November 2, 2017

Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation
10:11

Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation

Published on: January 3, 2020

Related Experiment Videos

Last Updated: May 30, 2026

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats
10:51

Chronic Transcranial Electrical Stimulation and Intracortical Recording in Rats

Published on: May 11, 2018

Transcranial Electrical Brain Stimulation in Alert Rodents
10:08

Transcranial Electrical Brain Stimulation in Alert Rodents

Published on: November 2, 2017

Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation
10:11

Updated Technique for Reliable, Easy, and Tolerated Transcranial Electrical Stimulation Including Transcranial Direct Current Stimulation

Published on: January 3, 2020

  • tDCS after-effects are dependent on stimulation polarity, duration, and intensity.
  • Co-application with neuropharmacological agents can significantly alter or prolong tDCS effects.
  • tACS and tRNS can interfere with neuronal oscillations and induce neuroplastic effects.

    • Conclusions:

    • Non-invasive brain stimulation techniques like tDCS, tACS, and tRNS offer versatile methods for modulating brain function.
    • Optimizing stimulation parameters and considering pharmacological interactions are crucial for achieving desired neuroplastic outcomes.