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Updated: May 30, 2026

A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
Published on: October 26, 2020
Role of interventions for atherosclerotic renal artery stenoses
Vikram S Kashyap1, Fabrice Schneider, Jean-Baptiste Ricco
1Division of Vascular Surgery, University Hospitals Case Medical Center, Cleveland, OH, USA. vikram.kashyap@uhhospitals.org
Abstract:
The role of and indications for interventions for renal artery stenosis have long been a hot topic of debate. Despite numerous reports and studies over the years, there remain many unanswered questions. Among them are: Who should be intervened upon? What should be the objectives of intervention? What is the optimal mode of intervention? More recently, several randomized studies have attempted to answer some of these basic questions, but unfortunately have left many unanswered questions. In the following debate, the authors consider the existing literature and attempt to convince us that the majority, or the minority, of patients with renal artery stenoses should be intervened upon.
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