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Updated: May 30, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Cardiac resynchronization therapy for non-ischemic cardiomyopathy-immediate changes in QRS duration, with left bundle
Saurav Chatterjee1, Gunjan Guha, Joydeep Ghosh
1Dept of Internal Medicine, Maimonides Medical Center, Brooklyn, New York, USA. saurav.sphs@gmail.com
Background:
We evaluated mean QRS duration improvement immediately after cardiac resynchronization therapy (CRT) in patients with non-ischemic cardiomyopathy (NICM), with a left bundle branch block (LBBB) pattern on electrocardiogram (ECG), owing to obligatory right ventricular pacing or as a new finding; and to what extent.
Methods And Results:
We tabulated ECGs of 18 subjects, 24 hours before and after receiving CRT, for both groups. The percentage decreases of QRS duration in all groups were statistically similar (p<0.05). There was a significant negative correlation (p<0.05) between age and the percentage of the QRS decrease.
Conclusions:
The study showed a greater reduction in QRS duration with CRT for younger subjects.
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