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Updated: May 30, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
[Dispersion behavior of effective ingredients in Chinese medicine decoctions]
Mao-Lin Wan1, Li Liu, Hong-Fei Wu
1Anhui Province Key Laboratory of R&D of Chinese Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
Objective:
To research the disperse behavior of many Chinese medicine decoctions.
Methods:
Through the analysis of the dispersible attributes of 22 kinds of Chinese medicine decoctions including Radix Salviae Miltiorrhizae by means of turbidity, ultramicroscope and TEM, we found that a lot of nanometer particles existed in these decoctions after 4000 r/min centrifugation. Based on the model of Radix Salviae Miltiorrhizae, we analyzed the influence on the loss of effective ingredients by way of centrifugation, alcohol precipitation, flocculation and salting-out edulcoration.
Results:
The removal of infinite nanometer particles from these decoctions led to the greater loss of water-soluble and fat-soluble ingredients,and the latter accounts for the major loss.
Conclusion:
Oral liquid preparation of traditional Chinese medicine is a kind of nano-pharmaceutics with nanometer particles dispersed in the water as the carriers of effective ingredients in medicine.
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