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Updated: May 30, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
Published on: September 27, 2024
Fractionation: a new era in laser resurfacing
Nazanin Saedi1, Anthony Petelin, Christopher Zachary
1Department of Dermatology, University of California at Irvine, Box 340 Medical Sciences, Irvine, CA 92697, USA.
Abstract:
Fractional photothermolysis combines the benefits of fully ablative lasers with significantly reduced downtime and fewer complications. Skin is treated in a fractional manner, with narrow cylinders of tissue being thermally heated and normal adjacent skin left unaffected, and the fractional devices have shown effectiveness in treating a variety of conditions, especially scarring and photodamage. There are many devices that use fractional photothermolysis, and practitioners are becoming more adept at using optimal parameters to induce near CO(2) laser benefits. Fractionated lasers have become the cornerstone of a minimally invasive treatment regimen and have ushered in a new era of laser skin rejuvenation.

