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The Creation of a Rat Model for Osteosarcopenia via Ovariectomy
Published on: February 21, 2025
Current and future pharmacologic treatment of sarcopenia
Yves Rolland1, Graziano Onder, John E Morley
1Inserm U1027, University of Toulouse III, Avenue Jules Guesdes, France. rolland.y@chu-toulouse.fr
Abstract:
Sarcopenia is a complex multifactorial condition that can by treated with multimodal approaches. No pharmacologic agent to prevent or treat sarcopenia has been as efficacious as exercise (mainly resistance training) in combination with nutritional intervention (adequate protein and energy intake). However, performing resistance training sessions and following nutritional advice can be challenging, especially for frail, sarcopenic, elderly patients, and results remain only partial. Therefore, new pharmacologic agents may substantially reduce the functional decline in older people. This article reviews the new pharmacologic agents currently being assessed for treating sarcopenia.
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