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Related Concept Videos

Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility, suggesting a...
Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
Type II Diabetes II: Pathophysiology01:24

Type II Diabetes II: Pathophysiology

PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
Nephrotic Syndrome I : Introduction01:24

Nephrotic Syndrome I : Introduction

Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of fluid...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...

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Updated: May 30, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
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Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas

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Preeclampsia: pathophysiology and implications for care.

Nancy S Townsend1, Susan B Drummond

  • 1The Junior League Fetal Center at Vanderbilt, Vanderbilt University Medical Center, Nashville, TN 37232, USA. nancy.s.townsend@vanderbilt.edu

The Journal of Perinatal & Neonatal Nursing
|August 10, 2011
PubMed
Summary
This summary is machine-generated.

Preeclampsia, a common hypertensive disorder in pregnancy, poses significant risks to mothers and fetuses. Nurses need comprehensive knowledge for effective patient care and prevention of maternal mortality.

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Published on: November 20, 2015

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Last Updated: May 30, 2026

Disruption of the Mouse Blood-Brain Barrier by Small Extracellular Vesicles from Hypoxic Human Placentas
05:31

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Published on: January 26, 2024

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
07:36

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

Area of Science:

  • Obstetrics and Gynecology
  • Maternal Health Nursing

Background:

  • Hypertensive disorders of pregnancy, including preeclampsia, are common and a leading cause of maternal mortality.
  • The Joint Commission highlighted maternal mortality prevention, citing hypertensive disorders as a major factor.
  • Preeclampsia presents substantial risks to both maternal and fetal well-being.

Purpose of the Study:

  • To emphasize the critical need for nurses to understand preeclampsia.
  • To underscore the importance of comprehensive nursing knowledge in managing preeclampsia.
  • To promote safe patient care by enhancing nursing expertise in preeclampsia.

Main Methods:

  • Literature review on preeclampsia pathophysiology, assessment, and management.
  • Analysis of maternal mortality data related to hypertensive disorders.
  • Synthesis of current clinical guidelines and nursing best practices.

Main Results:

  • Preeclampsia requires detailed understanding of its mechanisms and clinical presentation.
  • Effective management necessitates knowledge of treatment protocols and potential complications.
  • Recurrence risks and long-term health implications must be considered in patient care plans.

Conclusions:

  • Nurses require in-depth knowledge of preeclampsia's pathophysiology, assessment, and management.
  • Understanding recurrence risk and long-term implications is vital for comprehensive care.
  • Enhanced nursing expertise contributes to improved maternal and fetal outcomes and patient safety.