Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Mammary Glands01:12

The Mammary Glands

The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
Each breast features a pigmented projection known as the nipple, through which milk emerges via closely spaced openings of ducts, referred to as lactiferous ducts. Surrounding the nipple is a circular pigmented area of skin named the areola, which appears rough due to...
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Cutaneous malignant melanoma: one single disease ?].

Revue medicale de Liege·2012
Same author

[The psoriasis--metabolic syndrome comorbidity, a complex multigenic disease].

Revue medicale de Liege·2012
Same author

[Staphylococcus and its counter-measures against epidermal antimicrobial peptides].

Revue medicale de Liege·2012
Same author

[Drug-related psoriasis].

Revue medicale de Liege·2012
Same author

[The thousand and one facets of skin stem cells. The future has found new roots].

Revue medicale de Liege·2012
Same author

[Metastatic melanoma: some hope from ipilimumab and vemurafenib].

Revue medicale de Liege·2012
Same journal

[Nature prescriptions and health promotion : sharing experience from primary care].

Revue medicale de Liege·2026
Same journal

[Eco-health: shared perspectives on primary care practice].

Revue medicale de Liege·2026
Same journal

[The strategic role of primary care in emerging diseases : surveillance, research, and preparedness].

Revue medicale de Liege·2026
Same journal

[Environmental impact of medicines and approaches for more eco responsible use].

Revue medicale de Liege·2026
Same journal

[Climate change and skin].

Revue medicale de Liege·2026
Same journal

[From Silent Spring to neuronal silence : pesticides and neurodegenerative diseases].

Revue medicale de Liege·2026
See all related articles

Related Experiment Video

Updated: May 30, 2026

Sectioning Mammary Gland Whole Mounts for Lesion Identification
09:22

Sectioning Mammary Gland Whole Mounts for Lesion Identification

Published on: July 24, 2017

[Mammary Paget's disease].

M A Reginster1, P Quatresooz, C Piérard-Franchimont

  • 1Service de Dermatopathologie, CHU de Liège, Belgique. marie-annick.reginster@chu.ulg.ac.be

Revue Medicale De Liege
|August 11, 2011
PubMed
Summary
This summary is machine-generated.

Mammary Paget's disease is a rare intraepithelial carcinoma affecting the nipple and areola, often linked to underlying breast cancer. Early diagnosis and surgical treatment are crucial for effective management.

More Related Videos

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
09:36

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Published on: October 16, 2010

Related Experiment Videos

Last Updated: May 30, 2026

Sectioning Mammary Gland Whole Mounts for Lesion Identification
09:22

Sectioning Mammary Gland Whole Mounts for Lesion Identification

Published on: July 24, 2017

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
13:35

Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction

Published on: May 17, 2024

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
09:36

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Published on: October 16, 2010

Area of Science:

  • Oncology
  • Dermatology
  • Pathology

Context:

  • Mammary Paget's disease is a rare intraepithelial carcinoma.
  • It primarily affects the nipple and areola region.
  • The condition typically occurs in middle-aged women.

Purpose:

  • To describe the key histopathologic and immunopathologic features of Mammary Paget's disease.
  • To emphasize the importance of early diagnosis in identifying associated underlying breast cancer.
  • To outline the principles of surgical treatment based on the characteristics of the primary tumor.

Summary:

  • Mammary Paget's disease presents as an intraepithelial carcinoma on the nipple and areola.
  • It is characterized by the presence of specific Paget's cells.
  • A frequent association with underlying galactophoric adenocarcinoma necessitates thorough investigation for deeper mammary carcinoma.

Impact:

  • Highlights the critical need for early detection and diagnosis of Mammary Paget's disease.
  • Underscores the link between this condition and underlying breast cancer, influencing treatment strategies.
  • Provides essential information for clinicians managing patients with Paget's disease of the breast.