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Screening and Isolation of C-Glycoside-Cleaving Intestinal Bacteria
Published on: February 28, 2025
Antioxidant and urease inhibitory C-glycosylflavonoids from Celtis africana
Shagufta Perveen1, Azza Muhammed El-Shafae, Areej Al-Taweel
1Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 2457, Riyadh 11451, Saudi Arabia. shakhan@ksu.edu.sa
Abstract:
Two new C-glycosylflavonoids celtisides A (1) and B (2) have been isolated from n-butanol-soluble fraction of Celtis africana, along with five known C-glycosylflavonoids vitexin (3), orientin (4), isoswertiajaponin (5), isoswertisin (6), and 2″-O-rhamnosyl vitexin (7) reported for the first time from this species. Their structures were assigned from 1D and 2D NMR spectra. These compounds were investigated for biological activities and showed significant antioxidant and urease inhibitory activities.
