Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Adrenergic Agonists: Mixed-Action Agents

Adrenergic Agonists: Mixed-Action Agents

Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate adrenoceptors and indirectly release stored neurotransmitters, amplifying the adrenergic response.
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...

Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

Direct-Acting Cholinergic Agonists: Chemistry and Structure-Activity Relationship

Cholinergic agonists or cholinomimetics mimic the action of acetylcholine to stimulate the parasympathetic nervous system. They are categorized into direct-acting and indirect-acting agents. The direct-acting cholinergic drugs induce the parasympathetic response by directly binding to the muscarinic or nicotine receptors. In comparison, the indirect-acting cholinergic drugs prevent acetylcholine hydrolysis, indirectly contributing to the extended parasympathetic response.
The direct-acting...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ribonucleic acid binding protein-mediated regulation of luteinizing hormone receptor expression in granulosa cells: relationship to sterol metabolism.

Molecular endocrinology (Baltimore, Md.)·2007

Same author

Psychological stress-induced oxidative stress as a model of sub-healthy condition and the effect of TCM.

Evidence-based complementary and alternative medicine : eCAM·2007

Same author

Overexpression of OsCOIN, a putative cold inducible zinc finger protein, increased tolerance to chilling, salt and drought, and enhanced proline level in rice.

Planta·2007

Same author

Edge-based scoring and searching method for identifying condition-responsive protein-protein interaction sub-network.

Bioinformatics (Oxford, England)·2007

Same author

[The value of long-term postoperative follow-up after curative resection of lung cancer and common problems associated with it].

Nihon Geka Gakkai zasshi·2007

Same author

Identification of a type III thioesterase reveals the function of an operon crucial for Mtb virulence.

Chemistry & biology·2007

Search research articles

Related Experiment Video

Updated: May 30, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

Published on: February 2, 2024

Chemical constituents from Eupatorium chinense.

Wen-Jing Wang¹, Ying Wang, Qin-Wen Zhang

¹Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.

Journal of Asian Natural Products Research

|August 12, 2011

Summary

Researchers identified three novel compounds from Eupatorium chinense roots: two monoterpenoid glycosides and a thiophen derivative. Structural elucidation was achieved through detailed spectroscopic and chemical analyses, expanding knowledge of plant-derived natural products.

Related Experiment Videos

Last Updated: May 30, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC

Published on: February 2, 2024

Area of Science:

Natural Product Chemistry
Phytochemistry
Organic Chemistry

Background:

Eupatorium chinense is a plant species known for its diverse secondary metabolites.
The isolation and characterization of novel compounds contribute to the understanding of plant chemical diversity.
Previous research may have indicated the presence of bioactive compounds in this species.

Purpose of the Study:

To isolate and elucidate the structures of new chemical entities from the roots of Eupatorium chinense.
To characterize novel monoterpenoid glycosides and thiophen derivatives.
To contribute to the phytochemical database of Eupatorium species.

Main Methods:

Extraction of compounds from Eupatorium chinense roots.
Isolation and purification using chromatographic techniques (e.g., column chromatography, HPLC).
Structure determination via extensive spectroscopic analyses (NMR, MS) and chemical methods.

Main Results:

Isolation of two new monoterpenoid glycosides: α-(E)-acaridiol 8-O-β-d-glucopyranoside (1) and α-(E)-acaridiol 9-O-β-d-glucopyranoside (2).
Isolation of a new thiophen derivative: 2-acetyl-3-hydroxy-5-(prop-1-ynyl)thiophen 3-O-β-d-glucopyranoside (3).
Confirmation of structures through comprehensive spectroscopic and chemical analyses.

Conclusions:

The study successfully identified and characterized three previously unknown compounds from Eupatorium chinense.
The findings expand the known chemical constituents of Eupatorium chinense, particularly monoterpenoid glycosides and thiophen derivatives.
The detailed structural information provides a basis for further investigation into the potential bioactivity of these novel compounds.