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The development of giant lipoma on the BCG vaccine caused scar

Serap Gunes Bilgili1, Ayse Serap Karadag, Mehmet Fethi Ceylan

  • 1Faculty of Medicine, Department of Dermatology, Yuzuncu Yil University, Van, Turkey. drserapgunes@yahoo.com

Cutaneous and Ocular Toxicology
|August 12, 2011
PubMed

Insights

A rare giant lipoma developed at a Bacillus Calmette-Guérin (BCG) vaccination scar in a child. This case highlights lipomas can grow significantly, even at vaccination sites, requiring surgical removal.

Area of Science:

  • Pediatric Oncology
  • Dermatology
  • Surgical Pathology

Background:

  • Lipomas are common pediatric soft-tissue tumors, typically small (1-2 cm).
  • Complications from Bacillus Calmette-Guérin (BCG) vaccination are documented.
  • Giant lipomas are exceptionally rare in children.

Observation:

  • A 14-month-old girl presented with a rapidly growing, painful left shoulder lesion causing restricted movement.
  • The lesion was located at the site of a previous BCG vaccination scar.
  • Clinical and histopathological examination confirmed a lipoma.

Findings:

  • The lipoma was unusually large, presenting as a giant mass.
  • Surgical resection was complete, with no recurrence observed over 12 months.
  • This represents the first reported case of a lipoma arising from a BCG vaccination scar.

Implications:

  • This case expands the differential diagnosis for pediatric soft-tissue masses.
  • It underscores the potential for unusual presentations of common childhood tumors.
  • Highlights the importance of considering iatrogenic or post-procedural origins for pediatric lesions.

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