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Updated: May 30, 2026
08:41
Organotypic Tissue Model Systems for Investigating Host-Pathogen Interactions In Vitro
Published on: March 28, 2025
Epithelial interleukin-8 responses to oral bacterial biofilms
R Peyyala1, S Kirakodu, K F Novak
1Center for Oral Health Research, College of Dentistry, University of Kentucky, 414 HSRB, 1095 VA Drive, Lexington, KY 40536, USA. rpeyy1@email.uky.edu
Clinical and Vaccine Immunology : CVI
|August 12, 2011
Abstract:
An in vitro model of bacterial biofilms on rigid gas-permeable contact lenses (RGPLs) was developed to challenge oral epithelial cells. This novel model provided seminal data on oral biofilm-host cell interactions, and with selected bacteria, the biofilms were more effective than their planktonic counterparts at stimulating host cell responses.
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