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Updated: May 30, 2026

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Rapid Colorimetric Assays to Qualitatively Distinguish RNA and DNA in Biomolecular Samples
Published on: February 4, 2013
Colourimetric and spectroscopic discrimination between nucleotides and nucleosides using para-sulfonato-calix[4]arene
Yannick Tauran1, Marie Grosso, Arnaud Brioude
1LMI CNRS UMR 5615, Univ. Lyon 1, Villeurbanne, F69622, France.
Abstract:
The complexation of nucleosides and nucleotides by hybrid nanoparticles capped by para-sulfonato-calix[4]arene shows clear discrimination between purine and pyrimidine based molecules. For the pyrimidine nucleotides there is appearance of a new absorption band around 550 nm, and a colour change from yellow to orange red and pink.

