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Updated: May 30, 2026

Simultaneous Detection of Different Antibody Classes in a Multiplexed Serological Test
Published on: July 14, 2023
[Suspected borreliosis - what's behind it?]
F Hanses1, F-X Audebert, T Glück
1Klinik und Poliklinik für Innere Medizin I, Klinikum der Universität Regensburg. frank.hanses@klinik.uni-r.de
Background And Objective:
Borreliosis may be associated with unspecific symptoms and thus not only cause difficulties in diagnosis but also lead to overdiagnosis.
Patients And Methods:
Data on 134 patients (mean age 47 [12 - 78] years, 51.5 % male) with suspected borreliosis presenting at the university hospital Regensburg were analyzed retrospectively.
Results:
The majority of patients had been adequately treated for borreliosis previously. 34 patients (25.4 %) had proven or possible borreliosis, 20 patients (14.9 %) presented for consultation only. Regarding the remaining 80 patients (59.7 %), in 36 (45 %) a rheumatologic, orthopedic or neurologic disease was found as causal for the presenting symptoms, in 44 (55 %) no somatic disease could be diagnosed.
Conclusion:
A careful differential diagnosis seems mandatory in patients with suspected borreliosis and persistent complaints.
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