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Primary Culture of Human Vestibular Schwannomas
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Abrikossoff tumor: does it origin in swchann cells? Case report
Mauro Tarallo1, Emanuele Cigna, Pasquale Fino
1Department of Dermatology and Plastic, Reconstructive and Aesthetic Surgery, University of Rome "Sapienza" Policlinico Umberto I, Rome, Italy.
Annali Italiani Di Chirurgia
|August 13, 2011
Summary
Abrikossoff tumor, a soft tissue neoplasm, typically originates from Schwann cells, as supported by S-100 expression. Complete physical examination is crucial for patients to detect associated tumors.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Abrikossoff tumor is a rare neoplasm affecting soft tissues, skin, and oral mucosa.
- While typically benign, 1-2% of cases are malignant with a fatal outcome.
- Multiple lesions occur in 5-25% of patients.
Observation:
- A 52-year-old male presented with a tongue lesion.
- Surgical excision was performed, and histopathology confirmed Abrikossoff tumor.
- S-100 protein expression was noted in the tumor cells.
Findings:
- The pathogenesis of Abrikossoff tumor remains debated, with theories including myogenic and neural origins.
- S-100 expression supports the hypothesis of Schwann cell origin.
- The tumor generally has a good prognosis.
Implications:
- Abrikossoff tumor likely originates from Schwann cells.
- Complete physical examination is vital to screen for multiple lesions and potential visceral involvement.
- Early detection and comprehensive evaluation are key for patient management.
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