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Diffuse large B-cell lymphoma with aberrant expression of the T-cell antigens CD2 and CD7
Nikhil A Sangle1, Archana M Agarwal, Kristi J Smock
1Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA. nikhil_sangle@yahoo.com
Abstract:
Diffuse large B-cell lymphoma is the most common type of non-Hodgkin lymphoma. Although, aberrant expression of a single T-cell-associated antigen (exclusive of CD5) on diffuse large B-cell lymphoma has occasionally been described in the literature, cases that show coexpression of ≥2 T-cell antigens on a well-documented case of diffuse large B-cell lymphoma are extremely rare. Here, we describe a well-characterized case of diffuse large B-cell lymphoma that showed aberrant coexpression of 2 T-cell-associated antigens, CD2 and CD7. Recognition of these types of cases is important to help ensure accurate diagnoses are made.
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