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Updated: May 30, 2026
03:23
Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
[Eosinophilic gastroenteritis with ascites: clinical case report].
Víctor Yep Gamarra1, Ana Matos Nova, Augusto Aldave Herrera
1Médico Ex Residente de Gastroenterología del Hospital Regional Docente de Trujillo-Perú.
Summary
Eosinophilic gastroenteritis, a rare condition of GI eosinophilic infiltration, can present unusually with ascites. This case highlights successful treatment with corticosteroids, offering hope for similar rare presentations.
Area of Science:
- Gastroenterology
- Immunology
- Internal Medicine
Background:
- Eosinophilic gastroenteritis (EG) is a rare gastrointestinal disorder characterized by eosinophilic infiltration of the GI tract.
- Clinical manifestations of EG are diverse, varying with the location and depth of eosinophilic involvement.
- Atopy is a common comorbidity associated with EG.
Observation:
- A patient with a history of atopy presented with ascites, peripheral eosinophilia, and chronic intermittent diarrhea.
- Endoscopic examination revealed severe multifocal erythematous gastritis.
- Ascitic fluid analysis demonstrated elevated white blood cell count with eosinophilia and a low serum-albumin ascites gradient (<1.1).
Findings:
- The patient's presentation mimicked other causes of ascites, underscoring the diagnostic challenge of EG.
- Peripheral eosinophilia and eosinophilic ascites are key indicators in diagnosing EG.
- A low SAAG in ascites suggests a non-portal hypertensive etiology.
Implications:
- This case emphasizes the importance of considering EG in patients with ascites and peripheral eosinophilia, especially those with a history of atopy.
- Prompt diagnosis and treatment with corticosteroids can lead to clinical remission.
- Further research into the varied presentations of EG is warranted to improve diagnostic strategies.
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