Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 30, 2026

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Published on: January 17, 2025

Absolute configuration of micromelin.

Hoong-Kun Fun, Ittipon Siridechakorn, Surat Laphookhieo

Acta Crystallographica. Section E, Structure Reports Online

|August 13, 2011

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Bis(ferrocenecarbaldehyde 4-methyl-thio-semicarbazonato-κN,S)zinc(II) methanol solvate.

Acta crystallographica. Section E, Structure reports online·2011

Same author

Poly[[diaqua-(3-carb-oxy-5-nitro-ben-zo-ato)(μ-5-nitro-benzene-1,3-dicarboxyl-ato)neodymium(III)] 2.5-hydrate].

Acta crystallographica. Section E, Structure reports online·2011

Same author

2-((E)-{2-[(E)-2,3-Dihydroxy-benzyl-ideneamino]-5-methyl-phen-yl}iminiometh-yl)-6-hydroxy-phenolate.

Acta crystallographica. Section E, Structure reports online·2011

Same author

Ethyl 4-butyl-amino-3-nitro-benzoate.

Acta crystallographica. Section E, Structure reports online·2011

Same author

(1Z)-1-(2,4-Dichloro-phen-yl)ethan-1-one semicarbazone.

Acta crystallographica. Section E, Structure reports online·2011

Same author

4-[(4-Fluoro-benzyl-idene)amino]-3-[1-(4-isobutyl-phen-yl)eth-yl]-1H-1,2,4-triazole-5(4H)-thione.

Acta crystallographica. Section E, Structure reports online·2011

This study identifies a coumarin compound isolated from Micromelum glanduliferum roots. Structural analysis reveals molecular conformations and intermolecular interactions in the crystal lattice.

Area of Science:

Natural Product Chemistry
Organic Chemistry
Crystallography

Background:

Micromelum glanduliferum is a plant species known for its potential medicinal properties.
Coumarins are a class of organic compounds with diverse biological activities.
Isolation and structural elucidation of natural products are crucial for discovering new therapeutic agents.

Purpose of the Study:

To isolate and characterize a coumarin compound from Micromelum glanduliferum.
To determine the crystal structure of the isolated coumarin.
To investigate the intermolecular interactions in the solid state.

Main Methods:

Isolation of the compound using chromatographic techniques.
Structure determination using X-ray crystallography.

More Related Videos

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)

Published on: May 8, 2020

A Simple Critical-sized Femoral Defect Model in Mice

A Simple Critical-sized Femoral Defect Model in Mice

Published on: March 15, 2015

Related Experiment Videos

Last Updated: May 30, 2026

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography

Published on: January 17, 2025

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)

Published on: May 8, 2020

A Simple Critical-sized Femoral Defect Model in Mice

A Simple Critical-sized Femoral Defect Model in Mice

Published on: March 15, 2015

Analysis of molecular conformation and crystal packing.

Main Results:

A coumarin compound, 7-methoxy-6-[(1R,2R,5R)-5-methyl-4-oxo-3,6-dioxabicyclo-[3.1.0]hexan-2-yl]-2H-chromen-2-one, was isolated.
The crystal structure revealed two molecules in the asymmetric unit with slight differences.
The furan ring exhibited a flattened envelope conformation.
Intermolecular C-H⋯O interactions and aromatic π-π stacking were observed.

Conclusions:

The study provides the first detailed structural characterization of this specific coumarin.
Understanding the crystal packing and intermolecular forces is important for structure-activity relationship studies.
The findings contribute to the knowledge of coumarins from the Micromelum genus.