Related Experiment Video
Updated: May 30, 2026
10:35
Production and Testing of Antimicrobial Peptides and Their Mimics
Published on: April 10, 2026
1-(Bromo-meth-yl)adamantane
Acta Crystallographica. Section E, Structure Reports Online
|August 13, 2011
Summary
This study reveals that the C(11)H(17)Br molecule exhibits mirror symmetry in its solid-state crystal structure. Molecular symmetry and weak van der Waals forces dictate its crystal packing arrangement.
Area of Science:
- Crystallography
- Solid-state chemistry
- Molecular structure
Background:
- Understanding molecular symmetry is crucial in solid-state chemistry.
- Crystal packing influences material properties.
- Van der Waals interactions play a role in stabilizing crystal lattices.
Purpose of the Study:
- To elucidate the crystallographic symmetry of the title compound, C(11)H(17)Br.
- To describe the molecular arrangement and interactions within the crystal structure.
- To analyze the factors contributing to the stability of the crystal packing.
Main Methods:
- Single-crystal X-ray diffraction analysis was performed.
- The crystallographic data was processed to determine molecular symmetry.
- Crystal structure was analyzed to identify intermolecular interactions.
Main Results:
- The title compound, C(11)H(17)Br, exhibits crystallographically imposed mirror symmetry in the solid state.
- Molecules are bisected by mirror planes parallel to the crystallographic ac plane.
- The crystal packing is primarily stabilized by weak, non-specific van der Waals interactions.
Conclusions:
- The solid-state structure of C(11)H(17)Br is characterized by molecular symmetry.
- The observed symmetry and weak intermolecular forces govern the crystal packing.
- This structural information provides a basis for understanding the physical properties of the compound.
Related Concept Videos
01:16Adrenergic Agonists: Chemistry and Structure-Activity Relationship
Adrenergic agonists' structure-activity relationship (SAR) determines their selectivity and efficacy. These agonists comprise a phenylethylamine moiety with an aromatic ring and an ethylamine side chain.
Aromatic ring substitutions: Substituting the aromatic ring with –OH groups at positions 3 and 4 yields catecholamines (e.g., epinephrine), which have a high affinity for adrenoceptors. Hydrogen bonding between –OH groups and receptors enhances adrenergic activity.
Separation of the aromatic...
Aromatic ring substitutions: Substituting the aromatic ring with –OH groups at positions 3 and 4 yields catecholamines (e.g., epinephrine), which have a high affinity for adrenoceptors. Hydrogen bonding between –OH groups and receptors enhances adrenergic activity.
Separation of the aromatic...
01:27Radical Substitution: Allylic Bromination
In organic synthesis, the formation of products can be altered by changing the reaction conditions. For example, a dibromo addition product is formed when propene is treated with bromine at room temperature. In contrast, propene undergoes allylic substitution in non-polar solvents at high temperatures to give 3-bromopropene. In order to avoid the addition reaction, the bromine concentration must be kept as low as possible throughout the reaction. This can be achieved using N-bromosuccinimide...
02:46Halogenation of Alkenes
Halogenation is the addition of chlorine or bromine across the double bond in an alkene to yield a vicinal dihalide. The reaction occurs in the presence of inert and non-nucleophilic solvents, such as methylene chloride, chloroform, or carbon tetrachloride.
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
02:41Formation of Halohydrin from Alkenes
An alkene, such as propene, reacts with bromine in the presence of water to yield a halohydrin. Halohydrins contain a halogen and a hydroxyl group attached to adjacent carbons. When the halogen is bromine, it is called a bromohydrin, while a chlorohydrin has chlorine as the halogen.
01:10Nomenclature of Aryl and Heterocyclic Amines
The simplest aromatic amine is phenylamine, which contains an –NH2 functionality directly attached to an aromatic ring. The name aniline is designated for this skeleton. As shown in Figure 1, the common names of the functionalized anilines involve prefixes ortho-, meta-, and para- to indicate the substitution position. Different functionalized aniline derivatives also have notable trivial names.
01:20Diazonium Group Substitution with Halogens and Cyanide: Sandmeyer and Schiemann Reactions
Arenediazonium substitution reactions occur when the diazonium group is substituted by various functional groups such as halides, hydroxyl, nitrile, etc. For instance, arenediazonium salts react with copper(I) salts of chloride, bromide, or cyanide to form corresponding aryl chlorides, bromides, and nitriles. These reactions are named Sandmeyer reactions. Although the mechanism of this reaction is complicated, as illustrated in Figure 1, they are believed to progress via an aryl copper...