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Updated: May 30, 2026
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Single-Cell Calcium Imaging for Studying the Activation of Calcium Ion Channels
Published on: December 13, 2024
A near-infrared fluorescent calcium probe: a new tool for intracellular multicolour Ca2+ imaging
Akihiro Matsui1, Keitaro Umezawa, Yutaka Shindo
1Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1, Hiyoshi, Yokohama 223-8522, Japan.
Chemical Communications (Cambridge, England)
|August 13, 2011
Abstract:
We report a novel near-infrared fluorescent calcium probe (KFCA), which has good optical properties such as intense NIR fluorescence emission (670 nm, QY: 0.24), excellent ON/OFF ratio (120-fold), and good wavelength-compatibility with visible-light-emissive fluorophores (Fluo-4, DsRed2), and which is applicable for real-time dual-colour intracellular Ca(2+) imaging.
