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Related Experiment Video

Updated: May 30, 2026

Neuro-rehabilitation Approach for Sudden Sensorineural Hearing Loss
09:44

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Published on: January 25, 2016

Clarithromycin induced reversible sensorineural hearing loss.

J K Hajiioannou1, V Florou, P Kousoulis

  • 1ENT Department of General Hospital of Nikea, Piraeus, Greece.

B-ENT
|August 16, 2011
PubMed
Summary
This summary is machine-generated.

Clarithromycin can cause reversible hearing loss in pregnant women. Prompt drug cessation and steroid treatment restored normal hearing in a reported case.

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Area of Science:

  • Otolaryngology
  • Pharmacology

Background:

  • Macrolide antibiotics, including clarithromycin, are widely used but can have rare ototoxic side effects.
  • While newer macrolides are generally considered safer, ototoxicity associated with clarithromycin warrants continued investigation.

Observation:

  • A case report details a young pregnant woman experiencing sensorineural hearing loss after taking clarithromycin.
  • The patient's hearing impairment resolved after discontinuing the antibiotic and receiving a brief course of low-dose steroids.

Findings:

  • This case highlights the potential for clarithromycin to induce reversible sensorineural hearing loss.
  • The findings contribute to the understanding of clarithromycin-induced ototoxicity, a rare but significant adverse effect.

Implications:

  • Clinicians should consider clarithromycin ototoxicity in patients presenting with hearing loss, especially during pregnancy.
  • A comprehensive otologic history and baseline audiogram are recommended for patients at risk before prescribing macrolides.