[Pseudoangiomatous spindle cell lipoma: about six cases]

Pseudoangiomatous spindle cell lipoma (PASCL) is a rare variant of spindle cell lipoma. Nine cases have been previously described in the literature. In this retrospective study, we report six cases reviewed in the department of pathology at the Bergonié Institute between 01/01/1987 and 31/12/2009.

Clinical and histological data were reviewed. A standard histological study was realized and immunochemistry was performed with smooth muscle actin (SMA), desmin, epithelial membran antigen (EMA), S 100 protein, CD34, CD31, MDM2, CDK4.

All patients were male and median age was 52. Median size was 3cm. We report four atypical locations: cheek, finger, elbow and jaw.

In our series, the frequency of PASCL was 1,25% of all spindle cell lipomas. Histological and immunohistochemical aspects are identical to those observed in the literature.

The pattern of PASCL is typical, particularly with the positivity of CD34, which is stronly suggestive of diagnosis.