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Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[Pseudoangiomatous spindle cell lipoma: about six cases]
Fouad Zouaidia1, Jean-Michel Coindre
1Département de pathologie, institut Bergonié, 229, cours de l'Argonne, 33076 Bordeaux, France. fouad_z@hotmail.com
Annales De Pathologie
|August 16, 2011
Summary
Pseudoangiomatous spindle cell lipoma (PASCL) is a rare tumor. This study details six new cases, highlighting typical histological and immunohistochemical features, especially CD34 positivity, aiding diagnosis.
Area of Science:
- Dermatopathology
- Oncology
- Surgical Pathology
Context:
- Pseudoangiomatous spindle cell lipoma (PASCL) is a rare variant of spindle cell lipoma.
- Only nine cases have been previously reported in the literature.
- This study reviews six additional cases from 1987-2009.
Purpose:
- To describe the clinicopathological features of PASCL.
- To evaluate the diagnostic utility of immunohistochemistry in PASCL.
- To determine the frequency of PASCL among spindle cell lipomas.
Summary:
- Six cases of PASCL were reviewed, all occurring in males with a median age of 52.
- The median tumor size was 3cm, with four cases presenting in atypical locations (cheek, finger, elbow, jaw).
- Histological and immunohistochemical findings, particularly CD34 positivity, were consistent with previous reports and strongly suggestive of diagnosis.
Impact:
- This study expands the known cases of PASCL, contributing to a better understanding of this rare lipoma variant.
- The findings reinforce the importance of specific immunohistochemical markers, such as CD34, for accurate PASCL diagnosis.
- The reported atypical locations broaden the differential diagnosis for lesions in these sites.
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