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Related Concept Videos

Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
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Advanced Glycation End-Products Sensitize Human Sensory-Like Neuron Cells to Capsaicin-Induced Calcium Influx
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The capsaicin 8% patch for peripheral neuropathic pain.

Janice England1, Till Wagner, Kai-Uwe Kern

  • 1The Christie NHS Foundation Trust, Manchester, UK.

British Journal of Nursing (Mark Allen Publishing)
|August 16, 2011
PubMed
Summary

The capsaicin 8% patch offers prolonged pain relief for neuropathic pain. Optimal application technique and patient management are key to maximizing its therapeutic benefits and improving quality of life.

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Area of Science:

  • Neurology
  • Dermatology
  • Pain Management

Background:

  • Neuropathic pain affects up to 8% of UK adults, significantly impacting quality of life.
  • This condition is often challenging to treat effectively.
  • The capsaicin 8% patch targets peripheral neuropathic pain at its source.

Purpose of the Study:

  • To describe the optimal application procedure for the capsaicin 8% patch based on real-world clinical experience.
  • To provide recommendations for maximizing the therapeutic benefit of the capsaicin 8% patch.
  • To address key aspects of patch application, including patient management and post-treatment care.

Main Methods:

  • The authors, experienced health professionals, detail their clinical experience with the capsaicin 8% patch.
  • The article outlines the optimal patch application procedure.
  • Recommendations are provided for enhancing treatment efficacy and patient experience.

Main Results:

  • A single 30- or 60-minute application of the capsaicin 8% patch can provide pain relief for up to 3 months.
  • Adherence to the application procedure is crucial for effective treatment.
  • The article offers practical insights into managing application-associated discomfort and post-treatment care.

Conclusions:

  • Optimizing the capsaicin 8% patch application procedure is essential for maximizing patient benefit.
  • Effective patient management and appropriate treatment settings enhance therapeutic outcomes.
  • This guide aims to help clinicians maximize the benefits of this novel treatment option for neuropathic pain.