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Updated: May 30, 2026

Preparation and Observation of Thick Biological Samples by Scanning Transmission Electron Tomography
Published on: March 12, 2017
New views of materials through aberration-corrected scanning transmission electron microscopy
1Oak Ridge National Laboratory, Materials Science and Technology Division, Oak Ridge, TN 37830-6071, USA. pennycooksj@ornl.gov
Advanced scanning transmission electron microscopes (STEM) now offer record resolution and high efficiency for spectroscopy. These improvements provide new insights into materials physics, particularly complex oxides.
Area of Science:
- Materials Science
- Physics
- Microscopy
Background:
- Scanning transmission electron microscopy (STEM) capabilities have been significantly advanced.
- Correction of third-order and fifth-order aberrations has been successfully achieved.
- These advancements enhance resolution and spectroscopic efficiency.
Purpose of the Study:
- To review recent advancements in STEM technology.
- To highlight the impact of aberration correction on STEM performance.
- To explore new research directions enabled by enhanced STEM capabilities, focusing on complex oxides.
Main Methods:
- Review of existing literature and case studies.
- Focus on aberration correction techniques in STEM.
- Analysis of applications in materials physics, particularly complex oxides.
Main Results:
- Achieved record resolution in STEM imaging.
- Enabled near 100% efficiency for electron energy loss spectroscopy (EELS).
- Facilitated higher currents for two-dimensional spectrum imaging.
Conclusions:
- STEM's intrinsic advantages (incoherent imaging, simultaneous data collection) are now leveraged more effectively.
- New insights into materials physics are being generated, especially in complex oxides.
- Future research directions are opening up due to these technological leaps.
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