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Updated: May 30, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Critical care and cirrhosis: outcome and benefit
Julia Wendon1, William Bernal, Chris Willars
1Institute of Liver Studies, Kings College Hospital, Denmark Hill, London, UK. julia.wendon@kcl.ac.uk
Purpose Of Review:
The incidence of cirrhosis is growing steadily and this cohort of patients will present in ever-greater numbers to critical care with acute decompensation, usually secondary to an inter-current event or following elective surgery. This review examines the evidence for treatment options and outcomes.
Recent Findings:
Outcome of cirrhotics presenting with end-organ dysfunction is steadily improving and their outcomes are not as poor as sometimes suggested. Treatment options for variceal bleeding and renal dysfunction are evolving and outcomes improving.
Summary:
Critical care support should be offered to patients with cirrhosis and in high-risk variceal bleed patients transhepatic portosystemic shunt should be considered.
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