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Related Concept Videos

Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
Drugs Acting on Autonomic Ganglia: Stimulants01:23

Drugs Acting on Autonomic Ganglia: Stimulants


Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating sympathetic or...
Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Nursing Interventions I: Taxonomy of Nursing Interventions01:03

Nursing Interventions I: Taxonomy of Nursing Interventions

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Related Experiment Video

Updated: May 30, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
07:51

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder

Published on: June 18, 2018

Pharmacologic intervention in habitual smoking.

I Coleman1

  • 1Medical Management, Ochsner Clinic.

Ochsner Journal
|August 17, 2011
PubMed
Summary

Smoking cessation is challenging, with only 6% success. Nicotine replacement therapy and bupropion, a non-nicotine antidepressant, are effective aids. Both treatments double the success rate compared to placebo.

Area of Science:

  • Public Health
  • Pharmacology
  • Addiction Medicine

Background:

  • Smoking cessation is a major public health goal due to significant health risks.
  • Millions attempt to quit smoking annually, but success rates remain low at approximately 6% globally.
  • Nicotine addiction drives continued tobacco use by enhancing neurotransmitter release in the brain's reward pathways.

Purpose of the Study:

  • To review the efficacy of smoking cessation aids.
  • To compare nicotine replacement therapy (NRT) with bupropion for smoking cessation.
  • To inform strategies for improving quit rates among smokers.

Main Methods:

  • Literature review of smoking cessation interventions.
  • Analysis of clinical trial data for NRT and bupropion.

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Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking
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Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking

Published on: August 6, 2013

Related Experiment Videos

Last Updated: May 30, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
07:51

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder

Published on: June 18, 2018

Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking
14:21

Creating Dynamic Images of Short-lived Dopamine Fluctuations with lp-ntPET: Dopamine Movies of Cigarette Smoking

Published on: August 6, 2013

  • Comparison of treatment efficacy against placebo.

    • Main Results:

    • Nicotine replacement therapy (available as gum, patch, inhaler, nasal spray) helps manage withdrawal symptoms.
    • Bupropion, a non-nicotine antidepressant, functions by blocking serotonin and norepinephrine reuptake.
    • Both NRT and bupropion demonstrate efficacy, proving twice as effective as placebo in aiding smoking cessation.

    Conclusions:

    • Pharmacological interventions significantly improve smoking cessation success rates.
    • Both nicotine replacement therapy and bupropion offer effective options for smokers seeking to quit.
    • Further research and accessible treatments are crucial for public health initiatives targeting smoking cessation.