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Solid-state Graft Copolymer Electrolytes for Lithium Battery Applications
Published on: August 12, 2013
Effect of lithium on serum electrolytes.
P R Geetha1, S M Channabasavanna, B S Rama Rao
1Research Associate IGMR Research Project, National Institute of Mental Health and Neurosciences, Bangalore-560029.
Indian Journal of Psychiatry
|August 18, 2011
Summary
Lithium treatment for manic depressive psychosis did not alter serum calcium, magnesium, phosphate, or protein levels over three months. This study found no significant electrolyte or protein changes in patients undergoing lithium therapy.
Area of Science:
- Psychiatry
- Clinical Pharmacology
- Biochemistry
Background:
- Manic depressive psychosis (now known as bipolar disorder) is a mood disorder.
- Lithium is a common treatment for bipolar disorder.
- The impact of lithium on serum electrolytes and proteins requires ongoing investigation.
Purpose of the Study:
- To investigate the effect of lithium on serum levels of calcium, magnesium, phosphates, and proteins in patients with manic depressive psychosis.
- To determine if long-term lithium treatment causes significant fluctuations in these key biochemical markers.
Main Methods:
- A cohort of 26 patients diagnosed with manic depressive psychosis was enrolled.
- Patients received lithium treatment for a duration of three months.
- Serum levels of calcium, magnesium, phosphates, and proteins were measured repeatedly throughout the study period.
Main Results:
- No statistically significant changes were observed in the serum levels of calcium during the three-month study.
- Serum levels of magnesium, phosphates, and proteins remained stable and showed no significant alterations.
- Repeated measurements confirmed the absence of notable electrolyte or protein level fluctuations attributable to lithium treatment.
Conclusions:
- Three months of lithium treatment in patients with manic depressive psychosis does not lead to significant changes in serum calcium, magnesium, phosphate, or protein levels.
- Lithium therapy appears to maintain biochemical stability concerning these specific electrolytes and proteins.
- Further research may explore longer-term effects or interactions with other factors.
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