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Updated: May 30, 2026

A Plate-Based Assay for the Measurement of Endogenous Monoamine Release in Acute Brain Slices
Published on: August 11, 2021
Suicidal ideation and biogenic amines in depression
V Palaniappan1, V Ramachandran, O Somasundaram
1Asst. Professor, Department of Psychiatry, Madras Medical College and Institute of Mental Health, Madras-600 010.
Abstract:
This report is based on the study of 40 depressives in an attempt to explore the possible association between the suicidal ideas and the biogenic amines. The severity of suicidal ideas was measured on Hamilton Depressive Rating Scale and their amine metabolites were measured (MHFG, HVA and 5 HIAA) in urine and C.S.F. It was observed that the level of 5 HIAA, and Serotonin (5 HT) was more related to suicidal ideas and was inversely related. The probable associations between these are discussed.
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