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Diabetic neuropathy.

D A Greene1, A F Sima, M A Pfeifer

  • 1Department of Internal Medicine, University of Michigan, Ann Arbor 48109.

Annual Review of Medicine
|January 1, 1990
PubMed
Summary
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Diabetic neuropathy is a common complication of diabetes, leading to significant limb amputations and patient morbidity. Early diagnosis and management, including glucose control and foot care, are crucial for preventing severe outcomes.

Area of Science:

  • Neurology
  • Endocrinology
  • Diabetology

Background:

  • Diabetic neuropathy is the most common peripheral neuropathy globally.
  • It is a significant cause of morbidity and limb amputations in diabetic patients.
  • The precise pathogenetic mechanisms underlying diabetic neuropathy are not fully understood.

Purpose of the Study:

  • To summarize the current understanding of diabetic neuropathy.
  • To highlight the importance of early diagnosis and management strategies.
  • To emphasize the role of glucose control and complication avoidance.

Main Methods:

  • Review of existing literature on diabetic neuropathy.
  • Analysis of pathogenetic mechanisms.
  • Evaluation of current therapeutic approaches.

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Main Results:

  • Diabetic neuropathy is a frequent complication of diabetes mellitus.
  • Hyperglycemia and insulin deficiency are implicated in its development.
  • Effective management involves early detection and comprehensive care.

Conclusions:

  • Diabetic neuropathy necessitates prompt diagnosis and exclusion of other neuropathies.
  • Prudent glycemic control is essential for managing diabetic neuropathy.
  • Preventing secondary complications through aggressive foot care and patient education is vital.