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Updated: May 30, 2026

Catheter-based Endovascular Angioplasty for Fibrosing Mediastinitis-associated Pulmonary Vein Stenosis
Published on: August 26, 2025
Massive air embolism in a Fontan patient
Gregory S Matte1, Barry D Kussman, Joseph W Wagner
1Department of Cardiac Surgery, Children's Hospital Boston, Boston, Massachusetts 02115, USA. gregory.matte@cardio.chboston.org
A pressurized cardiotomy reservoir during cardiopulmonary bypass can cause air emboli in Fontan circulation patients. Proper venting is crucial to prevent this dangerous complication in congenital heart disease surgery.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Pediatric Cardiology
Background:
- Cardiopulmonary bypass commonly utilizes integrated hard shell cardiotomy and venous reservoirs for congenital heart disease (CHD) patients.
- Proper venting of these reservoirs is critical to prevent system pressurization, which can lead to complications.
Observation:
- A case of air embolism occurred due to retrograde air propulsion through the venous line.
- This event was secondary to a pressurized cardiotomy reservoir in a patient with Fontan circulation.
Findings:
- Pressurized sealed cardiotomy events have been linked to vacuum-assisted venous drainage system issues and general improper venting.
- The study describes the specific mechanism of cardiotomy reservoir pressurization.
- The reported scenario was successfully simulated using a mock circuit to understand the pathophysiology.
Implications:
- Highlights the critical importance of adequate venting in cardiotomy reservoirs during cardiopulmonary bypass for CHD.
- Underscores the potential for severe complications like air embolism in Fontan patients if reservoirs are not properly managed.
- Provides insights for refining safety protocols and equipment design in pediatric cardiac surgery.
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