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Alternate drugs
A M Adelman1, M P Daly, R J Michocki
1Department of Family Medicine, School of Medicine, University of Maryland, Baltimore.
Clinics in Geriatric Medicine
|May 1, 1990
Summary
When prescribing medications for older adults, prioritize efficacy, safety, and cost. Consider alternative therapies and the potential for no drug treatment as the best option for elderly patients.
Area of Science:
- Geriatric Medicine
- Clinical Pharmacology
Background:
- Polypharmacy and adverse drug events are significant concerns in elderly patients.
- Age-related physiological changes can alter drug pharmacokinetics and pharmacodynamics.
Purpose of the Study:
- To outline key principles for selecting optimal drug therapy in elderly patients.
- To discuss the role of alternative pharmacologic and non-pharmacologic interventions.
Main Methods:
- Review of established principles in geriatric pharmacotherapy.
- Consideration of factors influencing drug selection for the elderly.
Main Results:
- Efficacy, side effect profile, drug interactions, and cost are critical factors.
- Non-pharmacologic or alternative drug therapies may be preferable in certain cases.
- Continuous reassessment of treatment necessity is essential.
Conclusions:
- Individualized drug selection is paramount for safe and effective geriatric care.
- A comprehensive approach considering all patient-specific factors ensures optimal therapeutic outcomes.