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Published on: June 10, 2025
Prediction of emergent heart failure death by semi-quantitative triage risk stratification
Harriette G C Van Spall1, Clare Atzema, Michael J Schull
1Population Health Research Institute, Hamilton Health Science and McMaster University, Hamilton, Canada.
Insights
The Canadian Triage Acuity Scale (CTAS) effectively predicts early death in emergency department heart failure patients. Higher CTAS scores indicate increased mortality risk, especially when considering comorbidities.
Area of Science:
- Emergency Medicine
- Cardiology
- Health Services Research
Background:
- Generic triage tools are used in emergency departments but lack validation for acute heart failure (HF) patients.
- Predicting short-term mortality risk in HF patients is crucial for timely intervention.
Purpose of the Study:
- To evaluate the Canadian Triage Acuity Scale (CTAS) for predicting early death in emergency department (ED) patients with acute heart failure (HF).
Main Methods:
- Retrospective analysis of 68,380 HF patients presenting to an Ontario ED between April 2003 and March 2007.
- Utilized National Ambulatory Care Reporting System and vital statistics databases to track outcomes.
- Assessed CTAS scores, vital signs (oxygen saturation, respiratory rate), mode of arrival, and comorbidities.
Main Results:
- Early mortality rates at 1-day and 7-days increased significantly with higher CTAS scores (CTAS 1 showing highest risk).
- CTAS 1, low oxygen saturation, rapid respiratory rate, and paramedic arrival predicted triage-critical status.
- CTAS demonstrated good discrimination for ED and 1-day death, with improved prediction when incorporating comorbidities.
Conclusions:
- The CTAS, primarily based on respiratory factors, effectively predicts emergent death in acute heart failure patients presenting to the ED.
- Incorporating comorbidities further enhances the predictive accuracy of the CTAS for mortality risk in this population.
Objectives:
Generic triage risk assessments are widely used in the emergency department (ED), but have not been validated for prediction of short-term risk among patients with acute heart failure (HF). Our objective was to evaluate the Canadian Triage Acuity Scale (CTAS) for prediction of early death among HF patients.
Methods:
We included patients presenting with HF to an ED in Ontario from Apr 2003 to Mar 2007. We used the National Ambulatory Care Reporting System and vital statistics databases to examine care and outcomes.
Results:
Among 68,380 patients (76±12 years, 49.4% men), early mortality was stratified with death rates of 9.9%, 1.9%, 0.9%, and 0.5% at 1-day, and 17.2%, 5.9%, 3.8%, and 2.5% at 7-days, for CTAS 1, 2, 3, and 4-5, respectively. Compared to lower acuity (CTAS 4-5) patients, adjusted odds ratios (aOR) for 1-day death were 1.32 (95%CI; 0.93-1.88; p = 0.12) for CTAS 3, 2.41 (95%CI; 1.71-3.40; p<0.001) for CTAS 2, and highest for CTAS 1: 9.06 (95%CI; 6.28-13.06; p<0.001). Predictors of triage-critical (CTAS 1) status included oxygen saturation <90% (aOR 5.92, 95%CI; 3.09-11.81; p<0.001), respiratory rate >24 breaths/minute (aOR 1.96, 95%CI; 1.05-3.67; p = 0.034), and arrival by paramedic (aOR 3.52, 95%CI; 1.70-8.02; p = 0.001). While age/sex-adjusted CTAS score provided good discrimination for ED (c-statistic = 0.817) and 1-day (c-statistic = 0.724) death, mortality prediction was improved further after accounting for cardiac and non-cardiac co-morbidities (c-statistics 0.882 and 0.810, respectively; both p<0.001).
Conclusions:
A semi-quantitative triage acuity scale assigned at ED presentation and based largely on respiratory factors predicted emergent death among HF patients.
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