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Updated: May 30, 2026
Porphyrin-Modified Beads for Use as Compensation Controls in Flow Cytometry
Published on: March 24, 2023
Imidazole-modified porphyrin as a pH-responsive sensitizer for cancer photodynamic therapy
Xianchun Zhu1, Wentong Lu, Yazhou Zhang
1Department of Chemistry and Biochemistry, Jackson State University, Jackson, MS 39211, USA.
Abstract:
5,10,15,20-Tetrakis(N-(2-(1H-imidazol-4-yl)ethyl)benzamide)porphyrin produced twice as many singlet oxygen ((1)O(2)) molecules at pH 5.0 (quantum yield 0.53 ± 0.01) than at pH 7.4, whereas the (1)O(2) quenching rate was reduced by a factor of 2.5 for a pH change from 7.4 to 5.0.
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