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Related Concept Videos

Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...

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Articles linked to this work by shared authors, journal, and citation graph.

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[Myocardial infarction and acute coronary syndrome: definitions, classification, and diagnostic criteria].

Arkhiv patologii·2015
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[Clinical and morphological aspects of infectious endocarditis].

Klinicheskaia meditsina·2015
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[Injuries to myocardium in infectious endocarditis].

Klinicheskaia meditsina·2014
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[Development of targeted indicators of quality in postmortem examination].

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[Standards of postmortem studies and services: a new normative basis of postmortem service].

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Related Experiment Video

Updated: May 30, 2026

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
03:45

Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model

Published on: August 8, 2022

[Primary (idiopathic) cardiomyopathies].

L V Kakturskiĭ

    Arkhiv Patologii
    |August 23, 2011
    PubMed
    Summary

    This lecture details the clinical and morphological features of primary cardiomyopathies. It covers macroscopic, histological, and ultrastructural changes in these heart muscle diseases.

    Area of Science:

    • Cardiology
    • Pathology
    • Histology

    Context:

    • Primary cardiomyopathies are a group of heart muscle diseases of unknown cause.
    • Understanding their characteristics is crucial for diagnosis and management.

    Purpose:

    • To provide a comprehensive overview of the clinical and morphological features of primary cardiomyopathies.
    • To illustrate the macroscopic, histological, and ultrastructural changes associated with different forms of these conditions.

    Summary:

    • The lecture discusses the clinical presentation and various forms of primary (idiopathic) cardiomyopathies.
    • Detailed macroscopic, histological, and ultrastructural findings are presented for each type.

    Impact:

    • Enhances understanding of primary cardiomyopathies for clinicians and researchers.

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    Last Updated: May 30, 2026

    Investigating the Pathogenesis of MYH7 Mutation Gly823Glu in Familial Hypertrophic Cardiomyopathy using a Mouse Model
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    An Approach to Study Shape-Dependent Transcriptomics at a Single Cell Level
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  • Aids in the accurate diagnosis and classification of heart muscle diseases.