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Updated: May 30, 2026

Inducement and Evaluation of a Murine Model of Experimental Myopia
Published on: January 22, 2019
The effect of genetic factors on the occurrence of myopia
Damian Czepita1, Artur Mojsa, Maria Ustianowska
1Department of Ophthalmology, Pomeranian Medical Academy, Szczecin, Poland. czepita@pro.onet.pl
Purpose:
The aim of this study was to investigate on a large population if and how genetic factors have an influence on the occurrence of myopia.
Material And Methods:
A total of 5533 students were examined (2659 boys and 2874 girls, in age 6 18 years, mean age 11.9, S.D. 3.2). The examination included retinoscopy under cycloplegia induced with 1% tropicamide. Myopia was defined as a spherical equivalent of at least -0.5 dioptres. The students and their parents completed a questionnaire on the child's family history of myopia. Data analysis was performed using chi-squared test; p-values of < 0.05 were considered statistically significant.
Results:
It was found that myopia occurs more often in students whose father (p < 0.001), mother (p < 0.001) or siblings (p < 0.0001) have myopia. A relation between the occurrence of myopia in grandparents and grandchildren was not observed (p > 0.05).
Conclusions:
The obtained results indicate that genetic factors have a significant effect on the occurrence of myopia.
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