Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Two-Dimensional Force System01:20

Two-Dimensional Force System

A two-dimensional system in mechanical engineering involves the analysis of motion and forces in a plane. A two-dimensional force vector can be resolved into its components as:
Calibration Curves: Linear Least Squares01:20

Calibration Curves: Linear Least Squares

A calibration curve is a plot of the instrument's response against a series of known concentrations of a substance. This curve is used to set the instrument response levels, using the substance and its concentrations as standards. Alternatively, or additionally, an equation is fitted to the calibration curve plot and subsequently used to calculate the unknown concentrations of other samples reliably.
For data that follow a straight line, the standard method for fitting is the linear...
Three-Dimensional Force System01:30

Three-Dimensional Force System

In mechanical engineering, a three-dimensional force system is a system of forces acting in three dimensions, with forces applied along the x, y, and z coordinate axes. The three-dimensional force system is an important concept in mechanical engineering, as it allows engineers to understand and analyze the behavior of objects and structures in three dimensions. By understanding the forces acting on a system, engineers can design more efficient and effective mechanical systems that can withstand...
Two-Dimensional Force System: Problem Solving01:29

Two-Dimensional Force System: Problem Solving

Solving problems related to two-dimensional force systems is an essential aspect of mechanics and engineering. By applying the principles of vector analysis and force equilibrium, one can determine the effect of multiple forces acting on an object in a two-dimensional space.
The first step to solving a two-dimensional force system problem is to draw a free-body diagram of the object under consideration. This diagram helps identify all the external forces acting on the object, including their...
Three-Dimensional Force System:Problem Solving01:30

Three-Dimensional Force System:Problem Solving

A three-dimensional force system refers to a scenario in which three forces act simultaneously in three different directions. This type of problem is commonly encountered in physics and engineering, where it is necessary to calculate the resultant force on the system, which can then be used to predict or analyze the behavior of the object or structure under consideration.
To solve a three-dimensional force system, first resolve each force into its respective scalar components. Do this using...
Indeterminate Structure01:18

Indeterminate Structure

Indeterminate structures refer to structures where internal forces and reactions cannot be determined using only the equations of static equilibrium.  Indeterminate structures have more unknown forces and reaction forces than equations of static equilibrium that can be used to determine them. Indeterminate structures are often used in engineering to create complex, efficient, and aesthetically pleasing structures. There are various types of indeterminate structures used in engineering and some...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Biological Differences between EGFR ex19del and ex21L858R-Preclinical Models Using an Engineered Pair of Isogenic NSCLC Cell Lines with CRISPR Engineering].

Gan to kagaku ryoho. Cancer & chemotherapy·2025
Same author

The phospholipolytically active neurotoxin Vipoxin induces changes of the mechanical properties of breast epithelial cells.

Biochimica et biophysica acta. Biomembranes·2025
Same author

Current status and influencing factors of social support for main caregivers of children with traumatic brain injury: a cross-sectional survey.

Italian journal of pediatrics·2025
Same author

Canonical androgen response element motifs are tumor suppressive regulatory elements in the prostate.

Nature communications·2024
Same author

Diffuse Large B-Cell Lymphoma in a Cynomolgus Monkey.

Journal of medical primatology·2024
Same author

AFM-IR of Electrohydrodynamically Printed PbS Quantum Dots: Quantifying Ligand Exchange at the Nanoscale.

Nano letters·2024

Related Experiment Video

Updated: May 30, 2026

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

Shape-independent lateral force calibration.

Evan V Anderson1, Saonti Chakraborty, Taylor Esformes

  • 1Physics Department, Worcester Polytechnic Institute, 100 Institute Road, Worcester, Massachussetts 01609, United States.

ACS Applied Materials & Interfaces
|August 23, 2011
PubMed
Summary
This summary is machine-generated.

A new, simple lateral force calibration method exploits the linear force-voltage relationship. This technique offers a faster, less damaging alternative for precise experimental comparisons.

More Related Videos

Use of Atomic Force Microscopy to Measure Mechanical Properties and Turgor Pressure of Plant Cells and Plant Tissues
11:18

Use of Atomic Force Microscopy to Measure Mechanical Properties and Turgor Pressure of Plant Cells and Plant Tissues

Published on: July 15, 2019

Extracting the Young's Modulus of Native Murine Pulmonary Basement Membranes from Atomic Force Microscopy Derived Force Maps
10:55

Extracting the Young's Modulus of Native Murine Pulmonary Basement Membranes from Atomic Force Microscopy Derived Force Maps

Published on: January 31, 2025

Related Experiment Videos

Last Updated: May 30, 2026

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements
08:50

High-Speed Magnetic Tweezers for Nanomechanical Measurements on Force-Sensitive Elements

Published on: May 12, 2023

Use of Atomic Force Microscopy to Measure Mechanical Properties and Turgor Pressure of Plant Cells and Plant Tissues
11:18

Use of Atomic Force Microscopy to Measure Mechanical Properties and Turgor Pressure of Plant Cells and Plant Tissues

Published on: July 15, 2019

Extracting the Young's Modulus of Native Murine Pulmonary Basement Membranes from Atomic Force Microscopy Derived Force Maps
10:55

Extracting the Young's Modulus of Native Murine Pulmonary Basement Membranes from Atomic Force Microscopy Derived Force Maps

Published on: January 31, 2025

Area of Science:

  • Atomic Force Microscopy
  • Nanotechnology
  • Surface Science

Background:

  • Lateral force calibration is crucial for quantitative AFM measurements.
  • Existing methods are often slow, costly, and can damage the AFM tip.

Purpose of the Study:

  • To develop a rapid, cost-effective, and non-damaging method for lateral force calibration.
  • To improve the precision and reliability of lateral force measurements in AFM.

Main Methods:

  • Exploiting the linear relationship between applied force and measured voltage.
  • Developing a calibration technique independent of sample and cantilever geometry.

Main Results:

  • Achieved better than 10% precision in lateral force calibration.
  • Eliminated common issues associated with traditional calibration methods.
  • Demonstrated a technique that is independent of sample and cantilever shapes.

Conclusions:

  • The presented method offers a significant improvement over current lateral force calibration techniques.
  • This advance facilitates more accurate and reproducible quantitative comparisons between AFM experiments.