Maternal weight gain in twin-twin transfusion syndrome
Mamoru Morikawa1, Takashi Yamada, Emi Hirayama-Kato
1Department of Obstetrics and Gynecology, Hokkaido University Graduate School of Medicine, Sapporo, Japan. mmamoru@med.hokudai.ac.jp
Acta Obstetricia Et Gynecologica Scandinavica
|August 23, 2011
Summary
Excessive maternal weight gain of at least 1.4 kg per week is linked to twin-twin transfusion syndrome (TTTS). This finding suggests a potential early indicator for this serious complication in monochorionic twin pregnancies.
Area of Science:
- Maternal-fetal medicine
- Perinatal outcomes
- High-risk pregnancies
Background:
- Twin-twin transfusion syndrome (TTTS) is a serious complication in monochorionic diamniotic twins.
- Early identification of risk factors for TTTS is crucial for timely intervention.
Purpose of the Study:
- To investigate the association between maternal weight gain patterns and the development of TTTS.
- To determine if specific rates of maternal weight gain can predict TTTS onset.
Main Methods:
- Retrospective observational study involving 124 women with monochorionic diamniotic twin pregnancies.
- Analysis of weekly maternal weight gain in relation to TTTS diagnosis.
- Sonographic confirmation of TTTS.
Main Results:
- A weekly maternal weight gain of ≥ 1.4 kg was observed in 45 women and preceded TTTS diagnosis in 78.6% of affected cases.
- Women with a weekly weight gain ≥ 1.4 kg had a significantly higher risk (RR, 6.44) of developing TTTS compared to those without.
- For women experiencing a first-time weekly gain ≥ 1.4 kg between weeks 16-27, the prospective risk of TTTS within three weeks was 52.0%.
Conclusions:
- Excessive maternal weight gain (≥ 1.4 kg/week) appears to be a potential indicator during the development of TTTS.
- Monitoring maternal weight gain may aid in the early detection of TTTS risk in high-risk twin pregnancies.
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