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Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
Published on: May 27, 2020
Spontaneous fMRI activity during resting wakefulness and sleep
1Section for Advanced MRI, LFMI, NINDS, National Institutes of Health, Bethesda, MD, USA. jhd@helix.nih.gov
Progress in Brain Research
|August 23, 2011
Summary
Spontaneous brain activity detected via functional magnetic resonance imaging (fMRI) during rest and sleep reveals consistent patterns. This review explores the origins of this intrinsic brain activity and its relation to functional connectivity.
Area of Science:
- Neuroscience
- Cognitive Neuroscience
- Neuroimaging
Background:
- The brain exhibits continuous intrinsic activity even during resting states.
- Functional magnetic resonance imaging (fMRI) is a key tool for observing this spontaneous neural activity.
- This activity appears organized into distinct patterns related to functional connectivity.
Purpose of the Study:
- To review and discuss the potential sources of spontaneous fMRI activity.
- To enhance understanding of the brain's intrinsic functional architecture.
Main Methods:
- Review of existing literature on spontaneous fMRI activity.
- Analysis of studies conducted during both waking rest and sleep.
Main Results:
- Spontaneous fMRI activity is a consistent feature of brain function across different states.
- These patterns suggest an underlying, organized functional connectivity network.
- Multiple potential sources contribute to this observed activity.
Conclusions:
- Understanding spontaneous fMRI activity is crucial for interpreting brain function.
- Further research into the sources of this activity will elucidate brain organization and dynamics.
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