Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetic Ketoacidosis ll: Pathophysiology01:22

Diabetic Ketoacidosis ll: Pathophysiology

Diabetic ketoacidosis (DKA) is a metabolic emergency characterized by hyperglycemia, ketonemia, and metabolic acidosis. It results from severe insulin deficiency and an excess of counterregulatory hormones, leading to uncontrolled lipolysis, ketogenesis, and widespread electrolyte and fluid disturbances.Pathophysiology The central event in DKA is a profound loss of insulin action. Without insulin, glucose uptake in insulin-dependent tissues is impaired, while hepatic glucose production...
Diabetic Ketoacidosis l: Introduction01:25

Diabetic Ketoacidosis l: Introduction

DefinitionDiabetic ketoacidosis (DKA) is an acute, life-threatening complication of diabetes mellitus, characterized by a triad of hyperglycemia (blood glucose >250 mg/dL), ketonemia or ketonuria, and metabolic acidosis (arterial pH <7.30 and serum bicarbonate <18 mEq/L). It results from insulin deficiency combined with elevated levels of counterregulatory hormones—glucagon, catecholamines, cortisol, and growth hormone—leading to increased lipolysis, hepatic ketone production, and...
Metabolic States of the Body: The Postabsorptive State01:18

Metabolic States of the Body: The Postabsorptive State

The postabsorptive state usually starts about four hours after a meal and lasts until the next meal is eaten. During this time, the digestive system stops absorbing nutrients, and the body uses stored energy reserves to maintain stable blood glucose levels.
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Metabolic States of the Body: Fasting and Starvation01:24

Metabolic States of the Body: Fasting and Starvation

During the initial hours of fasting, the body uses up its glycogen stores as an energy source. Once these glycogen reserves are depleted, the body begins breaking down stored triglycerides and structural proteins. During this stage, glycerol becomes a key substrate for gluconeogenesis, while free fatty acids undergo beta-oxidation to provide energy for tissues, such as skeletal muscle. In the fasting state, the body spares protein breakdown as much as possible to conserve muscle and structural...
Overview of Metabolism01:40

Overview of Metabolism

Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Dietary Connections01:23

Dietary Connections

In biological systems, most metabolic pathways are interconnected. The cellular respiration processes that convert glucose to ATP—such as glycolysis, pyruvate oxidation, and the citric acid cycle—tie into those that break down other organic compounds. As a result, various foods—from apples to cheese to guacamole—end up as ATP. In addition to carbohydrates, food also contains proteins and lipids—such as cholesterol and fats. All of these organic compounds are used as energy sources to produce...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Ketogenic Diet: Three Decades Later.

Journal of child neurology·2026
Same author

Ketogenic diet therapy for epilepsy in conjunction with concurrent inflammatory bowel disease: Case series and recommendations.

Epilepsy research·2026
Same author

Concurrent use of ketogenic diet therapy and cannabidiol in children and adults with epilepsy: A multicenter retrospective cohort study.

Epilepsy research·2026
Same author

Clinical, practical, and psychosocial challenges of living with glucose transporter type 1 deficiency syndrome.

Seizure·2026
Same author

Classic or classical ketogenic diet? Definitions and nomenclature.

Epileptic disorders : international epilepsy journal with videotape·2025
Same author

The Role of Carnitine Monitoring and Supplementation in Children With Epilepsy on a Ketogenic Diet.

Journal of child neurology·2025

Related Experiment Video

Updated: May 30, 2026

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements
05:42

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements

Published on: January 7, 2019

Ketogenic diets: where do we go from here?

Eric H Kossoff1, J Helen Cross

  • 1The John M. Freeman Pediatric Epilepsy Center, Department of Neurology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA. ekossoff@jhmi.edu

Epilepsy Research
|August 23, 2011
PubMed
Summary
This summary is machine-generated.

This article summarizes discussions from a 2012 symposium on dietary treatments for neurologic disorders. Experts aimed to advance the field by focusing on critical issues and future research directions.

More Related Videos

Quantitative Determination of De Novo Fatty Acid Synthesis in Brown Adipose Tissue Using Deuterium Oxide
07:34

Quantitative Determination of De Novo Fatty Acid Synthesis in Brown Adipose Tissue Using Deuterium Oxide

Published on: May 12, 2023

A Model of Chronic Nutrient Infusion in the Rat
08:18

A Model of Chronic Nutrient Infusion in the Rat

Published on: August 14, 2013

Related Experiment Videos

Last Updated: May 30, 2026

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements
05:42

Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements

Published on: January 7, 2019

Quantitative Determination of De Novo Fatty Acid Synthesis in Brown Adipose Tissue Using Deuterium Oxide
07:34

Quantitative Determination of De Novo Fatty Acid Synthesis in Brown Adipose Tissue Using Deuterium Oxide

Published on: May 12, 2023

A Model of Chronic Nutrient Infusion in the Rat
08:18

A Model of Chronic Nutrient Infusion in the Rat

Published on: August 14, 2013

Area of Science:

  • Neurology
  • Nutrition Science
  • Dietary Interventions

Background:

  • The third biannual international symposium on dietary treatments for neurologic disorders convened in 2012.
  • A critical need exists to maintain momentum in advancing the field between symposia.
  • The symposium aimed to consolidate discussions and focus efforts on immediate future challenges.

Purpose of the Study:

  • To summarize key discussions from the symposium.
  • To identify critical issues requiring immediate attention in the field of dietary treatments for neurologic disorders.
  • To outline future research directions and collaborative goals.

Main Methods:

  • Group meetings were convened at the end of the 4-day symposium.
  • Discussions involved clinical researchers, basic scientists, dietitians, and parents.
  • The focus was on identifying critical issues and setting future goals.

Main Results:

  • Key issues requiring immediate attention were identified.
  • Collaborative goals were discussed among diverse stakeholders.
  • The article presents a summary of these discussions and outcomes.

Conclusions:

  • Continued focus and collaboration are essential for advancing dietary treatments for neurologic disorders.
  • The symposium successfully identified critical areas for future research and intervention.
  • A unified approach involving researchers, clinicians, and families is crucial for progress.