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Signaling of hypochlorous acid by selective deprotection of dithiane. [corrected]
Jiyoung Hwang1, Myung Gil Choi, Jihee Bae
1Department of Chemistry, Chung-Ang University, Seoul, 156-756, Korea.
Abstract:
The selective signaling of hypochlorous acid by dithiane-protected [corrected] pyrene-aldehyde was investigated. Dithiolane derivative of pyrene-aldehyde was efficiently deprotected by hypochlorous acid to its corresponding aldehyde, which resulted in a prominent UV-vis and turn-on type fluorescence signaling. The signaling was not affected by the presence of other common alkali, alkaline earth metal ions, and anions. Interference from Hg(2+) ions could be successfully circumvented by using Chelex-100 resin. Dithiane [corrected] also provided selectivity toward hypochlorous acid over other commonly used oxidant of hydrogen peroxide.
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