Related Experiment Video
Updated: May 30, 2026

11:42
Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers
Published on: June 20, 2019
Dendron-mediated self-assembly of highly PEGylated block copolymers: a modular nanocarrier platform
Jin Woo Bae1, Ryan M Pearson, Niladri Patra
1Department of Biopharmaceutical Sciences, University of Illinois at Chicago, 833 S. Wood St. Chicago, IL 60612, USA.
Abstract:
PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.

