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Related Concept Videos

High-Performance Liquid Chromatography: Types of Detectors01:15

High-Performance Liquid Chromatography: Types of Detectors

The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte properties and...
Atomic Absorption Spectroscopy: Lab01:21

Atomic Absorption Spectroscopy: Lab

For AAS measurements, samples must be introduced as clear solutions, often requiring extensive preliminary treatment to dissolve materials like soils, animal tissues, and minerals. Common methods for sample preparation include treatment with hot mineral acids, wet ashing, combustion in closed containers, high-temperature ashing, or fusion with reagents.
 Solutions containing organic solvents, such as low-molecular-mass alcohols, esters, or ketones, enhance absorbances by increasing nebulizer...
Precipitation Titration: Endpoint Detection Methods01:19

Precipitation Titration: Endpoint Detection Methods

In argentometric precipitation titrations, endpoints can be detected visually by the Mohr, Volhard, and Fajans methods. In the Mohr method, adding a soluble chromate indicator gives an initial yellow color to the analyte solution. As the titrant is added, the first excess of silver ions forms a red silver chromate precipitate, marking the endpoint. The solution pH should be maintained at about 8 by adding solid CaCO3.
In the Volhard method, a standard excess of AgNO3 is first added to the...
Development of Analytical Methods01:21

Development of Analytical Methods

An analytical methodology can be divided into four sequential steps: technique, method, procedure, and protocol. A technique is a scientific principle that rationalizes a specific phenomenon through chemical measurements. Adapting a technique for analyzing a sample of interest is termed a method. The procedure outlines the directions for performing the analysis via an analytical method. The protocol is the detailed guidelines on the procedure, which should be strictly followed to obtain the...
Qualitative Analysis01:10

Qualitative Analysis

Qualitative analysis is the process of identifying elements, ions, or compounds in an unknown sample. It is the first and most fundamental type of analysis based on the hierarchy of analytical goals. This hierarchy is significant as it provides a structured approach to scientific research, with qualitative analysis serving as the initial step, providing essential information before moving on to quantitative or other forms of analysis.
There are two main approaches to qualitative analysis:...
Sample Preparation for Analysis: Overview01:21

Sample Preparation for Analysis: Overview

Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...

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Related Experiment Video

Updated: May 30, 2026

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples
09:51

TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

Published on: September 19, 2025

Analytical chemistry: sweet solution to sensing.

Samuel K Sia, Curtis D Chin

    Nature Chemistry
    |August 24, 2011
    PubMed
    Summary
    This summary is machine-generated.

    New methods enable glucose meter technology to quantify a wider range of analytes beyond blood sugar. This innovation expands the utility of established diabetes monitoring tools for broader diagnostic applications.

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    Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
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    Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

    Published on: June 1, 2012

    Related Experiment Videos

    Last Updated: May 30, 2026

    TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples
    09:51

    TD-DFT Guided Advanced E-Eye Sensing Technique for On-site Quantification of Fe, Cr, F, and As in the Environmental, Biological, and Food Samples

    Published on: September 19, 2025

    Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
    08:19

    Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

    Published on: June 1, 2012

    Area of Science:

    • Biomedical Engineering
    • Analytical Chemistry
    • Point-of-Care Diagnostics

    Background:

    • Glucose meters are widely used for quantitative blood glucose measurement in diabetes management.
    • Existing glucose meter technology relies on electrochemical detection principles.

    Discussion:

    • This study presents a novel adaptation of glucose meter technology for quantifying diverse analytes.
    • The method leverages the established electrochemical sensing platform for broader applicability.

    Key Insights:

    • Proven glucose meter technology can be repurposed for measuring various non-glucose analytes.
    • This significantly expands the diagnostic potential of point-of-care devices.

    Outlook:

    • Potential for developing multi-analyte diagnostic tools using existing glucose meter infrastructure.
    • Future applications may include broader disease screening and monitoring beyond diabetes.